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Assignment: NURS6501 Advanced Pathophysiology Week 1 Discussion

NURS6501 Advanced Pathophysiology

Week 1 Discussion

Factors That Influence Disease

In clinical settings, some of the most common questions that patients ask are Why do I have this? What caused this disorder? Will it ever go away? These emotional questions can be difficult to ask and to answer. However, for patients to come to terms with their diagnoses and adhere to treatment plans, they must have an understanding of factors that might have caused, or continue to impact, their disorders. As an advanced practice nurse, it is important that you are able to explain disorders, associated alterations and symptoms, and changes that might occur within your patients’ bodies.

To Prepare

Review this week’s media presentation with Dr. Terry Buttaro. Reflect on the importance of developing an in-depth understanding of pathophysiology.

Select a disorder from the following list:

Adrenal insufficiency (Addison’s disease)


Cholelithiasis (gallstones)

Colon cancer

Cystic fibrosis


Nephrolithiasis (kidney stones)


Parkinson’s disease


Select one of the following patient factors: genetics, gender, ethnicity, age, or behavior. Reflect on how that factor might impact your selected disorder, as well as potential associated alterations and symptoms.

Identify the pathophysiology of the associated alterations, including the normal and altered cellular function. Consider both intra- and extra-cellular changes that occur.

By Day 3

Post a brief description of a patient scenario involving the disorder and the factor you selected. Explain how the factor might impact your selected disorder, as well as potential associated alterations and symptoms. Finally, explain the pathophysiology of the associated alterations, including changes in cellular function.

Note: For this Discussion, you are required to complete your initial post before you will be able to view and respond to your colleagues’ postings. Begin by clicking on the “Post to Discussion Question” link and then select “Create Thread” to complete your initial post. Remember, once you click on Submit, you cannot delete or edit your own posts, and you cannot post anonymously. Please check your post carefully before clicking on Submit!

Walden NURS6501 Advanced Pathophysiology Week 1 Quiz

Question 1

When completing this quiz, did you comply with Walden University’s Code of Conduct including the expectations for academic integrity?

Question 2

55-year-old male has swelling of the feet. Which of the following aided in development of swelling?

Question 3

The nurse is teaching staff about the most common cause of Down syndrome. What is the nurse describing?

Question 4

A patient has severe mental retardation caused by a deletion of part of chromosome 5. What genetic disorder will the nurse see documented in the chart?

Question 5

A nurse is teaching a patient with diabetes how glucose is transported from the blood to the cell. What type of transport system should the nurse discuss with the patient?

Question 6

Sodium and water accumulation in an injured cell are a direct result of:

Question 7

A patient wants to know the risk factors for Down syndrome. What is the nurse’s best response?

Question 8

An aide asks the nurse why people who have neurofibromatosis will show varying degrees of the disease. Which genetic principle should the nurse explain to the aide?

Question 9

When a patient asks what causes cystic fibrosis, how should the nurse respond? Cystic fibrosis is caused by an _____ gene.

Question 10

During childhood, the thymus decreases in size, and this is referred to as _____ atrophy.

Question 11

A nurse is discussing the movement of fluid across the arterial end of capillary membranes into the interstitial fluid surrounding the capillary. Which process of fluid movement is the nurse describing?

Question 12

A nurse is reviewing the pedigree chart. When checking for a proband, what is the nurse looking for?

Question 13

A newborn male is diagnosed with albinism based on skin, eye, and hair appearance. Which finding will support this diagnosis?

Question 14

A patient who has diarrhea receives a hypertonic saline solution intravenously to replace the sodium and chloride lost in the stool. What effect will this fluid replacement have on cells?

Question 15

Which of the following disorders is manifested primarily in males?

Question 16

A patient has a heart attack that leads to progressive cell injury that causes cell death with severe cell swelling and breakdown of organelles. What term would the nurse use to define this process?

Question 17

A runner has depleted all the oxygen available for muscle energy. Which of the following will facilitate his continued muscle performance?

Question 18

The early dilation (swelling) of the cell’s endoplasmic reticulum results in:

Question 19

After a geneticist talks to the patient about being a chromosomal mosaic, the patient asks the nurse what that means. How should the nurse respond? You may _____ genetic disease(s).

Question 20

What causes the rapid change in the resting membrane potential that initiates an action potential?

Question 21

A nurse is reading a chart and sees the term oncotic pressure. The nurse recalls that oncotic pressure (colloid osmotic pressure) is determined by:

Question 22

A 50-year-old male was recently diagnosed with Huntington disease. Transmission of this disease is associated with:

Question 23

A group of prison inmates developed tuberculosis following exposure to an infected inmate. On examination, tissues were soft and granular (like clumped cheese). Which of the following is the most likely cause?

Question 24

A 55-year-old male with a 30-year history of smoking is examined for respiratory disturbance. Examination of his airway (bronchial) reveals that stratified squamous epithelial cells have replaced the normal columnar ciliated cells. This type of cellular adaptation is called:

Question 25

A 12-year-old male is diagnosed with Klinefelter syndrome. His karyotype would reveal which of the following?

Question 26

How are potassium and sodium transported across plasma membranes?